The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2024
Filed:
Sep. 05, 2019
Chengdu Origin Biotechnology Limited Company, Sichuan, CN;
Peng He, Sichuan, CN;
Haiyan Li, Sichuan, CN;
Hai Zhao, Sichuan, CN;
Pei Huang, Sichuan, CN;
Xuechao Wang, Sichuan, CN;
Abstract
The present application provides a borate ester compound suitable for being used as a proteasome inhibitor, a preparation method and use thereof, and the compound has the following structure wherein, R, Ris asymmetric substituent in para-position, and Rand Rare both selected from the group consisting of halogen; and when Ris F, Ris not Cl; when Ris Cl, Ris not Br or F; and when Ris Br, Ris not Cl; X, Xis selected from the group consisting of hydroxyl, or Xand Xtogether form a substituted or unsubstituted 4 to 10 membered ring containing 1 to 4 heteroatoms being selected from the group consisting of O, N and S.