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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12157740 B1

PDFFull Text
Date of Patent:
Dec. 03, 2024

Filed:

Sep. 02, 2021

Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau

Applicant:

Nantneuro, Llc, Culver City, CA (US);

Inventors:

Varghese John, Culver City, CA (US);

Dale Bredesen, Culver City, CA (US);

Patricia Spilman, Culver City, CA (US);

Barbara Jagodzinska, Culver City, CA (US);

Assignee:

NantNeuro, LLC, Culver City, CA (US);

Attorney:

Umberg Zipser LLP

Primary Examiner:

Brian E McDowell

Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4439 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4439 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01); C07D 471/04 (2013.01);
Abstract

Pharmaceutical compounds, compositions, methods, and uses therefor are presented using selected triazolopyridines and triazolopyrimidines to inhibit or reduce phosphorylation of tau proteins or that act as antagonists of corticotropin-releasing factor. Viewed from another perspective, compounds, compositions, and methods are presented for treating or preventing symptoms of Alzheimer's disease by inhibiting or reducing the phosphorylation of tau proteins.

Find Patent Forward Citations

John, Varghese. (2024). Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau (U.S. Patent No. 12157740). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12157740

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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