The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2024
Filed:
Sep. 26, 2019
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Nathanael S. Gray, Boston, MA (US);
John M. Hatcher, Boston, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/136 (2006.01); C07C 211/44 (2006.01); C07D 471/22 (2006.01); C07D 487/22 (2006.01); C07D 498/22 (2006.01);
U.S. Cl.
CPC ...
C07D 471/22 (2013.01); C07D 487/22 (2013.01); C07D 498/22 (2013.01);
Abstract
Disclosed are compounds of formula (I) or (II): that inhibit ALK, TRKA, TRKB, TRKC and ROS1. Also disclosed are pharmaceutical compositions containing the compounds and methods of using the compounds to treat disease.