The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2024

Filed:

May. 08, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Shadi Dayeh, San Diego, CA (US);

Ren Liu, Albuquerque, NM (US);

Youngbin Tchoe, San Diego, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B81C 1/00 (2006.01); A61B 5/00 (2006.01); A61B 5/25 (2021.01); B81B 1/00 (2006.01);
U.S. Cl.
CPC ...
B81C 1/00111 (2013.01); A61B 5/0077 (2013.01); A61B 5/25 (2021.01); B81B 1/008 (2013.01); A61B 2562/0285 (2013.01); A61B 2562/046 (2013.01); A61B 2562/125 (2013.01); B81B 2203/04 (2013.01); B81C 2201/0132 (2013.01); B81C 2201/0178 (2013.01);
Abstract

A nanowire electrode array has a plurality of vertical nanowires extending from a substrate, each of the nanowires including a core of unitary first dielectric material that also covers the substrate and is unitary with the substrate. Each core has a sharp sub-100 nm diameter tip and a wider base, electrode leads on sidewalls to the tip of the nanowire, and second dielectric covering the electrode leads. The tips in the array can penetrate individual cells in cell culture, such as a mini-brain culture. The substrate can include a window for simultaneous optical imaging and electrophysiological recording.


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