The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2024

Filed:

Nov. 08, 2019
Applicant:

Lightcast Discovery Ltd, Cambridge, GB;

Inventors:

Tom Isaac, Cambridge, GB;

Cameron Frayling, Cambridge, GB;

Assignee:

LIGHTCAST DISCOVERY LTD, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 1/00 (2006.01); B01L 3/00 (2006.01); C12N 5/0797 (2010.01); C12N 13/00 (2006.01); G01N 15/14 (2006.01); G01N 15/1492 (2024.01); G01N 33/58 (2006.01); G01N 15/01 (2024.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502715 (2013.01); B01L 3/502784 (2013.01); C12N 5/0623 (2013.01); C12N 13/00 (2013.01); G01N 15/1484 (2013.01); G01N 15/1492 (2024.01); G01N 33/582 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/10 (2013.01); B01L 2400/0427 (2013.01); G01N 15/01 (2024.01); G01N 2015/1481 (2013.01);
Abstract

Devices, systems, and associated methods are provided for manipulating and/or determining one or more characteristics of cells contained within a biological sample. In particular a device and methods of use thereof are provided, the device comprising a sorting component configured to separate cell-containing microdroplets from empty ones into a population of cell-containing first microdroplets; a microdroplet manipulation component configured to manipulate the first microdroplets using real or virtual electrowetting electrodes, and an optical detection system configured to detect an optical signal from the microdroplets via the one or more detection windows.


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