The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2024
Filed:
Mar. 20, 2019
Universiteit Twente, Enschede, NL;
Jai Prakash, Enschede, NL;
Peter Van Hoogevest, Neustadt an der Weinstraße, DE;
Gerrit Storm, Utrecht, NL;
Universiteit Twente, Enschede, NL;
Abstract
A composition comprising a liposome comprising a first phospholipid comprising a C-C:0 fatty acid and a C-C:0 fatty acid with a c-terminal carboxyl or a carboxaldehyde group; a second phospholipid comprising a C-C:0 fatty acid and a C-C:0 fatty acid and a sterol. The first phospholipid is preferably a phosphatidylcholine. The second phospholipid is preferably HSPC and the sterol is preferably cholesterol. In some embodiments, the molar ratio of the respective ingredients is 2-3:5-6:2-3; preferably 2:6:2; or 3:5:2, respectively. The invention also relates to the use of this composition in the targeting of M2 macrophages.