The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2024

Filed:

Sep. 17, 2019
Applicants:

Tatiana Wolfe, Hilliard, OH (US);

Caio C. Quini, São Paulo, BR;

Philip J. Horner, Houston, TX (US);

Matthew K. Hogan, Houston, TX (US);

The Methodist Hospital, Houston, TX (US);

Inventors:

Tatiana Wolfe, Hilliard, OH (US);

Caio C. Quini, São Paulo, BR;

Philip J. Horner, Houston, TX (US);

Matthew K. Hogan, Houston, TX (US);

Assignee:

THE METHODIST HOSPITAL, Houston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/055 (2006.01); G01R 33/50 (2006.01); G01R 33/56 (2006.01); G01R 33/563 (2006.01); G16H 30/20 (2018.01); G16H 30/40 (2018.01);
U.S. Cl.
CPC ...
A61B 5/0042 (2013.01); A61B 5/055 (2013.01); G01R 33/50 (2013.01); G01R 33/5608 (2013.01); G01R 33/56341 (2013.01); G16H 30/20 (2018.01); G16H 30/40 (2018.01);
Abstract

The exemplified system and method facilitate an objective, non-invasive measurement of myelin quality and integrity in living brains based on isolation of myelin-specific magnetic relaxation constants in k-space. The system uses magnetic resonance (MR) signals to select signatures specific to, or associated with, myelin and its structure and to then encode the selected signatures into an image or model to which the quantitative myelin health information can be co-registered with 2D, 3D visualization, and tractography of the myelin-signal isolated MR information. The system also sets a model for digital hierarchical learning of biomedical signals in MR, and beyond, based on experimental data in which it executes the herein described signal isolation operations.


Find Patent Forward Citations

Loading…