The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

May. 30, 2019
Applicant:

Asymchem Life Science (Tianjin) Co., Ltd., Tianjin, CN;

Inventors:

Hao Hong, Morrisville, NC (US);

Gage James, Morrisville, NC (US);

Na Zhang, Tianjin, CN;

Fang Liu, Tianjin, CN;

Junjie Yan, Tianjin, CN;

Ye Liu, Tianjin, CN;

Zujian Wang, Tianjin, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C12N 9/10 (2006.01); C12P 13/00 (2006.01); C12P 17/12 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C12N 9/1096 (2013.01); C12P 17/12 (2013.01); C12Y 206/01 (2013.01);
Abstract

Provided are a transaminase mutant and a method for producing a chiral amine using the same. An amino acid sequence of the transaminase mutant is an amino acid sequence obtained by mutation occurred in an amino acid sequence as shown in SEQ ID NO: 1, and the mutation includes at least one of the following mutation sites: position 3, position 5, position 8, position 25, position 32, position 45, position 56, position 59, position 60, position 84, position 86, position 164, position 176, position 178, position 180, position 187, position 197, position 206, position 207, position 242, position 245, position 319 and position 324.


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