The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2024
Filed:
Jun. 17, 2022
Pfizer Inc., New York, NY (US);
Surabhi Srivatsa Srinivasan, San Francisco, CA (US);
Niranjana Nagarajan, Oakland, CA (US);
Siler Panowski, Berkeley, CA (US);
Yoon Park, Seoul, KR;
Tao Sai, Foster City, CA (US);
Barbra Sasu, San Francisco, CA (US);
Thomas Van Blarcom, Oakland, CA (US);
Mathilde Dusseaux, Creteil, FR;
Roman Galetto, Paris, FR;
Pfizer Inc., New York, NY (US);
Abstract
The disclosure provides CARs (CARs) that specifically bind to CD70. The disclosure further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The disclosure further relates to therapeutic methods for use of these CARs and engineered immune cells comprising these CARs for the treatment of a condition associated with malignant cells expressing CD70 (e.g., cancer).