The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Mar. 10, 2021
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Robert Anthony Blake, South San Francisco, CA (US);

Peter Dragovich, South San Francisco, CA (US);

Lewis J. Gazzard, South San Francisco, CA (US);

Susan Kaufman, South San Francisco, CA (US);

Tracy Kleinheinz, South San Francisco, CA (US);

Thomas Pillow, South San Francisco, CA (US);

Steven T. Staben, South San Francisco, CA (US);

Binqing Wei, South San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/14 (2006.01); A61P 35/00 (2006.01); C07D 495/16 (2006.01);
U.S. Cl.
CPC ...
C07D 495/14 (2013.01); A61P 35/00 (2018.01); C07D 495/16 (2013.01);
Abstract

The present disclosure relates to compounds and salts thereof that are useful for inhibiting target polypeptides and proteins, in particular, bromodomain (e.g., BRD4) proteins. Also disclosed are pharmaceutical compositions comprising the compounds, or a salt (e.g., a pharmaceutically acceptable salt) thereof, and methods of using such compounds and salts in the treatment of various bromodomain-mediated diseases or disorders.


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