The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Jun. 23, 2022
Applicant:

Dose Medical Corporation, San Clemente, CA (US);

Inventors:

Patrick Michael Hughes, Aliso Viejo, CA (US);

Ina Mustafaj, Irvine, CA (US);

Assignee:

DOSE MEDICAL CORPORATION, San Clemente, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/44 (2006.01); A61K 9/00 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); C08L 71/02 (2006.01);
U.S. Cl.
CPC ...
A61L 27/446 (2013.01); A61K 9/0048 (2013.01); A61K 9/0051 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2400/06 (2013.01); C08L 71/02 (2013.01);
Abstract

The present disclosure is directed to a composite implant for the sustained release of a therapeutic agent from a hydrogel matrix. The hydrogel matrix may be a cross-linked bioerodible polyethylene glycol (PEG) hydrogel with a therapeutic complex dispersed within the cross-linked bioerodible PEG hydrogel. The therapeutic complex may include a therapeutic agent in association with mesoporous silica particles. The composite implant is configured to be delivered to or implanted into an eye of a subject or patient. The composite implant may be used treat ocular disease in a subject or patient. Ocular diseases may be selected from at least one of neovascular age related macular degeneration (AMD), diabetic macular edema, or macular edema following retinal vein occlusion.


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