The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2024
Filed:
Nov. 02, 2018
Nanjing Shunxin Pharmaceutical Co., Ltd., Jiangsu, CN;
Chia Tai Tianqing Pharmaceutical Group Co., Ltd, Jiangsu, CN;
Jianwen Li, Jiangsu, CN;
Yanju Cheng, Jiangsu, CN;
Yingchun Li, Jiangsu, CN;
Wei Zhao, Jiangsu, CN;
Xiquan Zhang, Jiangsu, CN;
NANJING SHUNXIN PHARMACEUTICAL CO., LTD., Jiangsu, CN;
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD, Jiangsu, CN;
Abstract
The invention is in the field of antibody formulations, and particularly relates to a pharmaceutical composition of a humanized monoclonal anti-PD-L1 antibody, wherein the pharmaceutical composition comprises 1-150 mg/ml of the humanized monoclonal anti-PD-L1 antibody, a buffer at 3-50 mM, 2-150 mg/ml of an isotonic adjuster/stabilizer and 0.01-0.8 mg/ml of a surfactant, and has a pH of about 4.5-6.8. The formulations prevent antibody aggregates therein from increasing, while enabling better maintenance of the biological binding activity of the antibody for a long time.