The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Oct. 23, 2019
Applicant:

University of Limerick, Limerick, IE;

Inventors:

Jakki Cooney, County Cork, IE;

Todd Kagawa, Kailua, HI (US);

Ruth Cullen, County Cavan, IE;

Senan Behan, County Limerick, IE;

Brian Noonan, Boxford, MA (US);

Assignee:

UNIVERSITY OF LIMERICK, Limerick, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C12N 9/52 (2006.01);
U.S. Cl.
CPC ...
A61K 38/48 (2013.01); C12N 9/52 (2013.01);
Abstract

An isolated protease comprising a polypeptide having the structure is described: P-A-B5 in which P is a protease domain, A is an A-domain, and B is a B-domain, of a Group VII to XIII cell envelope protease (CEP), wherein the protease does not have a PA domain. An isolated protease according to Claim, selected from a wild-type Group VII to XIII cell envelope protease. The use of the protease as a medicament is treating immune dysregulation diseases is also described.


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