The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2024
Filed:
Nov. 30, 2020
Applicant:
National University Corporation Kumamoto University, Kumamoto, JP;
Inventors:
Takumi Era, Kumamoto, JP;
Takayuki Kiboku, Kumamoto, JP;
Assignee:
NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, Kumamoto, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/443 (2006.01); A61P 19/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/443 (2013.01); A61P 19/08 (2018.01);
Abstract
A pathological mechanism in FOP patients is further revealed, and development of a novel therapeutic drug, therapeutic method, diagnostic method, etc. utilizing an obtained finding is provided. The inventors have found a novel finding that in FOP, ectopic ossification, which occurs by an inflammation due to an injury, etc., is mediated by PAR1 to occur. From this finding, the inventors completed the present invention relating to a drug, etc. characterized by suppressing ectopic ossification in FOP by inhibiting PAR1.