The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Aug. 17, 2021
Applicant:

Genzyme Corporation, Cambridge, MA (US);

Inventors:

Nikolai Bukanov, Boston, MA (US);

Sarah Moreno, Dudley, MA (US);

Timothy E. Weeden, Sturbridge, MA (US);

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/439 (2006.01); A61K 31/137 (2006.01); A61K 31/166 (2006.01); A61K 45/06 (2006.01); A61P 13/12 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/439 (2013.01); A61K 31/137 (2013.01); A61K 31/166 (2013.01); A61K 45/06 (2013.01); A61P 13/12 (2018.01); G01N 33/6893 (2013.01); G01N 2333/4728 (2013.01); G01N 2800/347 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01);
Abstract

Provided herein are methods for determining the efficacy of treatment for polycystic kidney disease (PKD) in a patient, diagnosing PKD in a patient, staging PKD in a patient, and monitoring PKD in a patient. These methods include determining a single or multiple levels of AMBP. Also provided are kits that include an antibody specifically binds to AMBP protein and at least one antibody that specifically binds to an additional marker of PKD.


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