The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Feb. 10, 2022
Applicant:

Bioventures, Llc, Little Rock, AR (US);

Inventor:

Vladimir Pavlovich Zharov, Little Rock, AR (US);

Assignee:

Bioventures, LLC, Little Rock, AR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/02 (2006.01); A61B 8/08 (2006.01); A61B 18/00 (2006.01); A61B 18/20 (2006.01); A61K 49/22 (2006.01); G01N 15/14 (2024.01); G01N 15/1434 (2024.01); G01N 21/17 (2006.01); G01N 21/39 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0095 (2013.01); A61B 5/0059 (2013.01); A61B 5/02007 (2013.01); A61B 5/412 (2013.01); A61B 5/415 (2013.01); A61B 5/416 (2013.01); A61B 5/418 (2013.01); A61B 5/7278 (2013.01); A61B 18/20 (2013.01); A61K 49/22 (2013.01); G01N 21/1702 (2013.01); G01N 21/39 (2013.01); A61B 8/08 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/20351 (2017.05); A61B 2018/20357 (2017.05); A61B 2018/20361 (2017.05); A61B 2018/207 (2013.01); G01N 15/1425 (2013.01); G01N 15/1434 (2013.01); G01N 15/147 (2013.01); G01N 2015/1477 (2013.01); G01N 2201/0697 (2013.01);
Abstract

A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism detect the photoacoustic ultrasound waves emitted by target objects in response to their illumination by at least one pulse of laser energy delivered using at least one wavelength. The wavelengths of the laser light pulse may be varied to optimize the absorption of the laser energy by the target object. Target objects detected by the device may be unlabelled biological cells or cell products, contrast agents, or biological cells labeled with one or more contrast agents.


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