The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Jun. 17, 2021
City University of Hong Kong, Kowloon, HK;
Yusheng Xie, Kowloon, HK;
Rui Wang, Kowloon, HK;
Liang Zhang, Kowloon, HK;
Hongyan Sun, Kowloon, HK;
CITY UNIVERSITY OF HONG KONG, Kowloon, HK;
Abstract
The present invention relates to a compound for use in detecting 'reader' and “eraser” proteins of lysine lipoylation. The present invention provides an affinity-based probe, referred to herein as “KPlip”, capable of interrogating the lipoylated peptide/protein interactions under native cellular environments. The chemical probe allows for the identification of potential regulators of lysine lipoylation, thus uncovering new biology related to lipoylation. There is also provided a method of using the compound to identifying proteins that interact with lipoylated proteins.