The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2024

Filed:

Oct. 19, 2023
Applicant:

Nankai University, Tianjin, CN;

Inventors:

Deling Kong, Tianjin, CN;

Zhuangzhuang Yang, Tianjin, CN;

Songdi Wang, Tianjin, CN;

Assignee:

NANKAI UNIVERSITY, Tianjin, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 2500/32 (2013.01); C12N 2501/115 (2013.01); C12N 2501/165 (2013.01); C12N 2501/998 (2013.01); C12N 2513/00 (2013.01);
Abstract

A vascularized cardiac organoid with a chamber structure and its preparation method is presented. The cardiac organoids have a unique chamber structure, which includes a myocardium wall. Within the cardiac organoids, a vascular network is developed, enclosed within the myocardium wall. This vascular network is composed of endothelial cells surrounded by smooth muscle cells, forming a network of branched tubular structures. The presence of vasculature significantly promotes the arrangement of the myocardium, enhances the organization of the cardiac cytoskeleton, and promotes the consistency and beating frequency of cardiac cells. The vasculature facilitates the growth and size increase of the cardiac organoids.


Find Patent Forward Citations

Kong, Deling. (2024). Vascularized cardiac organoid with a chamber structure and its preparation method (U.S. Patent No. 12146163). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12146163

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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