The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Nov. 26, 2015
New Pharma Licence Holdings Limited, Valletta, MT;
Pamela Brown, Reading, GB;
Michael Dawson, Reading, GB;
Mona Simonovic, Reading, GB;
Steven Boakes, Reading, GB;
Esther Duperchy, Reading, GB;
Steven James Stanway, Ongar, GB;
Antoinette Wilson, Ongar, GB;
Stephen Frederick Moss, Ongar, GB;
SPERO THERAPEUTICS, INC., Cambridge, MA (US);
Abstract
The present invention provides a compound of formula (I), and its use in methods of treatment, including the treatment of bacterial infections. Methods for the preparation of the compound of formula (I) are also provided. The compound of formula (I) has the structure shown below, where —Rand —Rare each together with the carbonyl group and nitrogen alpha to the carbon to which it is attached an amino acid residue, except that R6 together with the carbonyl group and nitrogen alpha to the carbon to which it is attached is not a phenylalanine, leucine or valine residue and/or —Rtogether with the carbonyl group and nitrogen alpha to the carbon to which it is attached is not a leucine, iso-leucine, phenylalanine, threonine, valine or nor-valine residue, and -T, -A, -A, -Aand —Rare as discussed in the application: