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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12145994 B1

PDFFull Text
Date of Patent:
Nov. 19, 2024

Filed:

Feb. 18, 2021

Bispecific antigen binding molecules capable of specific binding to cd40 and to fap

Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Peter Bruenker, Schlieren, CH;

Alexander Bujotzek, Penzberg, DE;

Harald Duerr, Penzberg, DE;

Guy Georges, Penzberg, DE;

Christian Klein, Schlieren, CH;

Stephane Leclair, Penzberg, DE;

Moritz Rapp, Schlieren, CH;

Eva Carina Sum, Schlieren, CH;

Christine Trumpfheller, Schlieren, CH;

Pablo Umaña, Schlieren, CH;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:

Lawrence S. Graham

Primary Examiner:

Yunsoo Kim

Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61P 35/00 (2018.01); C07K 16/40 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/572 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/35 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/64 (2013.01); C07K 2317/71 (2013.01); C07K 2317/75 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The invention relates to novel bispecific antigen binding molecules, comprising (a) at least one antigen binding domain capable of specific binding to CD40, and (b) at least one antigen binding domain capable of specific binding to a target cell antigen, in particular Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.

Find Patent Forward Citations

Bruenker, Peter. (2024). Bispecific antigen binding molecules capable of specific binding to cd40 and to fap (U.S. Patent No. 12145994). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12145994

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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