The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Mar. 14, 2018
Applicant:
Sunshine Lake Pharma Co., Ltd., Guangdong, CN;
Inventors:
Chao Chen, Dongguan, CN;
Shushan Lin, Dongguan, CN;
Yu Li, Dongguan, CN;
Xiaofeng Chen, Dongguan, CN;
Liang Liu, Dongguan, CN;
Zheng Fu, Dongguan, CN;
Assignee:
SUNSHINE LAKE PHARMA CO., LTD., Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61P 3/04 (2006.01); C07K 14/50 (2006.01); C07K 14/605 (2006.01);
U.S. Cl.
CPC ...
C07K 14/605 (2013.01); A61P 3/04 (2018.01); C07K 14/50 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided is a fusion protein containing GLP-1 and FGF21 linked through an immunoglobulin Fc portion. Each of the GLP-1 and FGF21 can be substituted with its analogues or variants and, the Fc portion, which can be derived from IgG4, can include substitutions that further enhance the fusion protein's stability and activity. These fragments can be linked together through peptide linkers. The fusion protein can be used clinically to reduce glucose and lipid levels and body weight.