The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Feb. 09, 2018
Applicant:
University of Louisville Research Foundation, Inc., Louisville, KY (US);
Inventor:
Nobuyuki Matoba, Owensboro, KY (US);
Assignee:
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC., Louisville, KY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/36 (2006.01); A61K 38/00 (2006.01); A61P 1/00 (2006.01); A61P 11/00 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C07K 14/36 (2013.01); A61P 1/00 (2018.01); A61P 11/00 (2018.01); A61P 31/18 (2018.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01); C12N 15/8258 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
Polypeptides are provided that include an actinohivin variant polypeptide. The actinohivin variant polypeptide can be operably connected to an antibody fragment, such as a fragment crystallizable (Fc) region of immunoglobulin (Ig) G. Nucleic acid sequences, expression vectors, and transformed plant cells useful for producing the polypeptides are also provided. Further provided are methods for treating a viral infection or a cancer in a subject and include the step of administering the actinohivin variant polypeptide to the subject.