The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Jul. 15, 2021
Applicants:
The Regents of the University of California, Oakland, CA (US);
Atlasmedx, Inc., San Francisco, CA (US);
Inventors:
Csaba J. Peto, San Francisco, CA (US);
David M. Jablons, San Francisco, CA (US);
Tsze Tsang, El Cerrito, CA (US);
Hassan Lemjabbar-Alaoui, San Francisco, CA (US);
Assignees:
AtlasMedx, Inc., San Francisco, CA (US);
The Regents of the University of California, Oakland, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/10 (2006.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 407/14 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/10 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 407/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01);
Abstract
The application relates to phthalazine derivatives of formula (I) which are inhibitors of PARP1, PARP2 and/or tubulin and thus useful for the treatment of cancer. Also disclosed are pharmaceutical formulations containing such compounds, as well as combinations of these compounds with at least one additional therapeutic agent.