The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Apr. 19, 2021
Applicant:
Curtana Pharmaceuticals, Inc., Austin, TX (US);
Inventors:
Graham Beaton, San Diego, CA (US);
Stanton F. McHardy, Waring, TX (US);
Ambrosio Lopez, Jr., San Antonio, TX (US);
Bismarck Campos, San Antonio, TX (US);
Hua-Yu Leo Wang, San Antonio, TX (US);
Assignee:
CURTANA PHARMACEUTICALS, INC., Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/48 (2006.01); A61P 35/00 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 239/48 (2013.01); A61P 35/00 (2018.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01);
Abstract
Described herein are compounds and pharmaceutical compositions of phenyl-pyrimidinyl-urea derivatives, which inhibit the activity of Olig2. An example of a phenyl-pyrimidinyl-urea derivative has the following structure: Also described herein are methods using the Olig2 inhibitors for treating cancer and other diseases. The Olig2 inhibitors may be used to treat glioblastoma.