The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Jul. 23, 2020
Applicant:
Translate Bio, Inc., Lexington, MA (US);
Inventors:
Shrirang Karve, Lexington, MA (US);
Frank DeRosa, Lexington, MA (US);
Michael Heartlein, Lexington, MA (US);
Natalia Vargas Montoya, Lexington, MA (US);
Priyal Patel, Lexington, MA (US);
Ashish Sarode, Lexington, MA (US);
Assignee:
TRANSLATE BIO, INC., Lexington, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/107 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 9/1075 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 48/0041 (2013.01);
Abstract
The present invention provides an improved compositions and processes for preparing mRNA-loaded lipid nanoparticles (mRNA-LNPs). In some embodiments, the present invention provides mRNA-LNPs with exceptional stability and is particularly useful in cases where LNPs comprising low or no PEG-modified lipids are desired.