The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Jul. 13, 2021
Applicant:
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Inventors:
Hans-Georg Lerchen, Leverkusen, DE;
Anne-Sophie Rebstock, Champagne au Mont d'Or, FR;
Yolanda Cancho Grande, Leverkusen, DE;
Leo Marx, Wuppertal, DE;
Beatrix Stelte-Ludwig, Wülfrath, DE;
Carsten Terjung, Bochum, DE;
Christoph Mahlert, Wuppertal, DE;
Simone Greven, Dormagen, DE;
Anette Sommer, Berlin, DE;
Sandra Berndt, Hohen Neuendorf, DE;
Assignee:
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/4025 (2006.01); A61K 31/4439 (2006.01); A61K 47/65 (2017.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 31/4025 (2013.01); A61K 31/4439 (2013.01); A61K 47/65 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61K 47/6857 (2017.08); A61K 47/6863 (2017.08); A61K 47/6865 (2017.08); A61K 2300/00 (2013.01);
Abstract
The present invention relates to novel binder-prodrug conjugates (APDCs) where binders are conjugated with inactive precursor compounds of kinesin spindle protein inhibitors, and to antibody-drug conjugates ADCs and to processes for producing these APDCs and ADCs.