The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
May. 20, 2022
Applicant:
Aurobac Therapeutics Sas, Lyons, FR;
Inventors:
Michael Wittekind, Bainbridge Island, WA (US);
Raymond Schuch, Mountain Lakes, NJ (US);
Assignee:
Aurobac Therapeutics SAS, Lyons, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/47 (2006.01); A61K 9/00 (2006.01); A61K 31/7036 (2006.01); A61K 38/12 (2006.01); A61K 38/16 (2006.01); A61K 38/46 (2006.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01); C12N 9/36 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 9/0019 (2013.01); A61K 9/0073 (2013.01); A61K 31/7036 (2013.01); A61K 38/12 (2013.01); A61K 38/162 (2013.01); A61K 38/46 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C12N 9/2462 (2013.01); C12Y 302/01017 (2013.01); A61K 2121/00 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present disclosure relates to methods for restoring or augmenting bactericidal activity of an antibiotic in an organ or tissue in which pulmonary surfactant is present. More specifically, the present disclosure describes that inhibition of antibiotics due to environmental factors, such as the presence of pulmonary surfactant in an organ or tissue such as the respiratory epithelium can be sidestepped or overcome and the effectiveness of the antibiotic in that milieu restored or augmented by co-administration of an antibiotic and a lysin.