The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Apr. 06, 2023
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
George Georgiou, Austin, TX (US);
Everett Stone, Austin, TX (US);
John Blazeck, Austin, TX (US);
Christos Karamitros, Austin, TX (US);
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 38/46 (2006.01); A61K 47/60 (2017.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 38/46 (2013.01); A61K 47/60 (2017.08); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C12Y 307/01003 (2013.01);
Abstract
Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.