The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2024

Filed:

Jul. 30, 2019
Applicant:

The Penn State Research Foundation, University Park, PA (US);

Inventors:

Zhiwen Liu, State College, PA (US);

Jian Yang, State College, PA (US);

Yizhu Chen, Fremont, CA (US);

Dingbowen Wang, State College, PA (US);

Assignee:

The Penn State Research Foundation, University Park, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); A61B 1/04 (2006.01); A61K 49/00 (2006.01); G01N 21/88 (2006.01);
U.S. Cl.
CPC ...
A61B 1/043 (2013.01); A61K 49/0021 (2013.01); A61K 49/006 (2013.01); G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G01N 2021/6419 (2013.01); G01N 2021/6421 (2013.01); G01N 2021/6423 (2013.01); G01N 2021/6439 (2013.01); G01N 2021/8893 (2013.01);
Abstract

A spectrally encoded fluorescence imaging system includes a multi-wavelength excitation light source emitting excitation light for illuminating a sample, optical components for introducing spectral encoding to focus different wavelengths of the excitation light at different positions in the sample to generate fluorescence at different, spatial positions, and band-shifting florescence imaging probes exhibiting excitation-dependent emission band, causing the fluorescence generated at different spatial positions to exhibit different band shifts, such that image information is encoded in the band-shifted fluorescence spectrums for parallel detection by a spectrometer or arrayed detectors operable to resolve different wavelengths.


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