The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2024

Filed:

Nov. 30, 2016
Applicant:

Universitat Basel, Basel, CH;

Inventors:

Etienne Bucher, Beaucouze, CH;

Michael Thieme, Zollikon, CH;

Assignee:

UNIVERSITAT BASEL, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01H 3/04 (2006.01); A01H 1/06 (2006.01); C12N 15/01 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
A01H 1/06 (2013.01); A01H 3/04 (2013.01); C12N 15/01 (2013.01); C12N 15/8201 (2013.01); C12N 15/8216 (2013.01);
Abstract

A method for the mobilization of a transposable element is provided. The method comprises the steps of a) providing an inhibitor of DNA methylation, and/or an inhibitor of transcription, and b) contacting the inhibitor(s) with a cell comprising inactivated transposable elements, yielding a cell with mobilized transposable elements. In a second aspect of the invention a method for increasing the genetic and/or epigenetic variation in a plurality of eukaryotic organisms is provided. The method comprises the steps of i. providing an inhibitor of DNA methylation and/or an inhibitor of transcription, ii. contacting the organism with the inhibitor(s) and iii. propagating the organism.


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