The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2024
Filed:
Jun. 01, 2018
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Universite Paris Descartes, Paris, FR;
Assistance Publique—hopitaux DE Paris, Paris, FR;
Imagine—institut Des Maladies Genetiques Necker Enfants Malades, Paris, FR;
Annarita Miccio, Paris, FR;
Vasco Meneghini, Bretigny-sur-Orge, FR;
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Paris, FR;
UNIVERSITE PARIS DESCARTES, Paris, FR;
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS, Paris, FR;
IMAGINE—INSTITUT DES MALADIES GENETIQUES NECKER ENFANTS MALADES, Paris, FR;
Abstract
This invention relates to recombinant lentiviral vectors, compositions thereof, the use of the vectors or the compositions thereof, kits of parts comprising said vectors or compositions thereof and a catalytically active Cas9 or Cpf1 protein, methods for modifying the genome of a hematopoietic stem/progenitor cell (HSPC), and the HSPC obtainable by such methods.