The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2024
Filed:
Jul. 23, 2021
Applicant:
Synthego Corporation, Redwood City, CA (US);
Inventors:
Travis Maures, La Jolla, CA (US);
Jared Carlson-Stevermer, Burlingame, CA (US);
Sahil Joshi, Somerville, MA (US);
Reed Kelso, San Francisco, CA (US);
Anastasia Kadina, Sunnyvale, CA (US);
John Andrew Walker, II, San Leandro, CA (US);
Assignee:
Synthego Corporation, Redwood City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07F 9/655 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C07F 9/65522 (2013.01); C12N 2310/20 (2017.05); C12N 2310/321 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/53 (2013.01);
Abstract
Provided herein are polynucleotides and CRISPR effector proteins configured to be covalently bound together in a CRISPR complex. The polynucleotides can be further modified to modulate the activity of the CRISPR complex. Modification of the polynucleotide and CRISPR effector protein can be used to improve the efficacy of target binding and/or cleavage.