The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2024

Filed:

Apr. 20, 2020
Applicant:

Y-biologics Inc., Daejeon, KR;

Inventors:

Jae Bong Yoon, Daejeon, KR;

Eun Young Jeon, Daejeon, KR;

Gi Sun Baek, Daejeon, KR;

Seok Ho Yoo, Daejeon, KR;

Bum-Chan Park, Daejeon, KR;

Young Woo Park, Daejeon, KR;

Assignee:

Y-BIOLOGICS INC., Daejeon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 39/00 (2006.01); A61K 47/68 (2017.01); A61P 37/06 (2006.01); C12N 5/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61K 47/6845 (2017.08); A61P 37/06 (2018.01); C07K 16/241 (2013.01); C12N 5/0018 (2013.01); C12N 15/85 (2013.01); A61K 2039/5156 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C12N 2800/107 (2013.01);
Abstract

A bispecific antibody according to an embodiment of the present disclosure specifically binds to IL-17A and TNF-α. The bispecific antibody according to the present invention or an antigen binding fragment thereof exhibits high specificity for IL-17A and TNF-α and more favorable neutralization property compared to monospecific antibody of a prior art, and, by quickly suppressing inflammation and an immune response by inhibiting simultaneously IL-17 and TNF-α, it has an advantage of improving the treatment effect with lower dose.


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