The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2024
Filed:
Jul. 02, 2021
Applicant:
Xencor, Inc., Pasadena, CA (US);
Inventors:
Matthew J. Bernett, Monrovia, CA (US);
John Desjarlais, Altadena, CA (US);
Rajat Varma, Monrovia, CA (US);
Suzanne Schubbert, Long Beach, CA (US);
Juan Diaz, Anaheim Hills, CA (US);
Assignee:
Xencor, Inc., Pasadena, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); C07K 14/715 (2006.01); C07K 14/735 (2006.01); C07K 16/28 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); A61K 38/17 (2006.01); A61K 38/20 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70535 (2013.01); A61K 39/395 (2013.01); A61P 35/00 (2018.01); C07K 14/5443 (2013.01); C07K 14/7155 (2013.01); C07K 16/2803 (2013.01); C07K 16/2815 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); A61K 38/1774 (2013.01); A61K 38/2086 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/55 (2013.01); C07K 2317/74 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01);
Abstract
The present invention is directed to a novel targeted heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc fusion protein and an antigen binding domain Fc fusion proteins. In some instances, the antigen binding domain binds to CD8, NKG2A, or NKG2D.