The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2024

Filed:

Jun. 14, 2017
Applicant:

Cellply S.r.l., Bologna, IT;

Inventors:

Massimo Bocchi, Bologna, IT;

Andrea Faenza, Bologna, IT;

Laura Rocchi, Bologna, IT;

Dario Biscarini, Bologna, IT;

Nicola Pecorari, Bologna, IT;

Assignee:

Cellply S.R.L, Bologna, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 3/02 (2006.01); G01N 1/30 (2006.01); G01N 1/31 (2006.01); G01N 15/14 (2006.01); G01N 15/1433 (2024.01); G01N 33/50 (2006.01); G01N 35/10 (2006.01); G06T 7/00 (2017.01); G06V 20/69 (2022.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50273 (2013.01); B01L 3/0275 (2013.01); B01L 3/502715 (2013.01); G01N 1/30 (2013.01); G01N 1/31 (2013.01); G01N 15/1433 (2024.01); G01N 15/1484 (2013.01); G01N 33/5011 (2013.01); G01N 35/10 (2013.01); G01N 35/1011 (2013.01); G06T 7/0012 (2013.01); G06V 20/698 (2022.01); B01L 2200/027 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/06 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0861 (2013.01); B01L 2400/04 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1493 (2013.01); G01N 2015/1497 (2013.01); G01N 2500/10 (2013.01); G06T 7/0014 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30072 (2013.01); G06T 2207/30242 (2013.01);
Abstract

A method for analysis of biological samples, implemented in a reversed open microwell system which includes an array of open microwells, a microchannel, an input port for reagents and/or biological samples and an output port. The ports are in microfluidic communication with the microchannel. The microchannel has a cross-section area of micrometric dimensions and provides fluid to the microwells. The microwell system is inserted in an automated management system that includes: an incubator at controlled temperature, humidity and CO2, fluid dispensing system, phase-contrast and fluorescence image acquisition. A kit introduces fluids in a microfluidic device that includes a tip. A microfluidic device and system include a microchannel and an input region having a vertical channel. The tip and the vertical channel are dimensioned to produce an interference coupling. A discharge region includes: a discharge container connected with the microfluidic device through a discharge channel and an output port.


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