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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12138350 B1

PDFFull Text
Date of Patent:
Nov. 12, 2024

Filed:

Feb. 09, 2016

Method of producing a extruded composition

Applicants:

Cubic Pharmaceuticals Ltd., Kent, GB;

Delta Pharmaceuticals Ltd., Kent, GB;

Inventors:

Dennis Douroumis, Kent, GB;

Mohammed Maniruzzaman, Kent, GB;

Saumil Kiritkumar Bhatt, Kent, GB;

Anwar Ali, Kent, GB;

Arun Jangra, Kent, GB;

Assignees:

Cubic Pharmaceuticals Ltd., Kent, GB;

Delta Pharmaceuticals Ltd., Kent, GB;

Attorneys:

Julie K. Staple

Dinsmore & Shohl LLP

Primary Examiner:

Patricia Duffy

Assistant Examiner:

Garen Gotfredson

Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61J 3/10 (2006.01); A61K 9/14 (2006.01); A61K 31/00 (2006.01); A61K 31/192 (2006.01); A61K 33/12 (2006.01); A61K 47/32 (2006.01); B29B 9/00 (2006.01); B29C 48/00 (2019.01); B29C 48/05 (2019.01); B29B 9/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2095 (2013.01); A61J 3/10 (2013.01); A61K 9/143 (2013.01); A61K 9/20 (2013.01); A61K 31/00 (2013.01); A61K 31/192 (2013.01); A61K 33/12 (2013.01); A61K 47/32 (2013.01); B29B 9/00 (2013.01); B29C 48/0011 (2019.02); B29C 48/05 (2019.02); B29B 9/06 (2013.01);
Abstract

The present invention relates to a method of producing a direct compression tablet composition comprising the step of processing ibuprofen, a hydrophilic polymer, and an inorganic excipient by an extrusion process to produce an extruded composition in which the ibuprofen forms a solid dispersion/solution within the hydrophilic polymer. The invention is particularly useful in preparing oral dissolvable tablets. Also provided are composition comprising an inorganic excipient and ibuprofen within a hydrophilic polymer.

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