The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2024

Filed:

Sep. 26, 2018
Applicant:

Inozyme Pharma, Inc., Boston, MA (US);

Inventors:

Tayeba Khan, Lexington, MA (US);

Andre Marozsan, Killingworth, CT (US);

Kim Askew, Lincoln, MA (US);

Assignee:

Inozyme Pharma, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61P 9/10 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); A61P 9/10 (2018.01); C07K 19/00 (2013.01); A61K 9/0019 (2013.01); A61K 45/06 (2013.01); C12Y 301/04001 (2013.01);
Abstract

The present invention provides methods for improving cardiovascular function in a human patient (e.g., reducing hypertension), as well as methods of treating a cardiovascular disease, by administering a recombinant human soluble ectonucleotide pyrophosphatase phosphodiesterase (hsNPP1), active fragment or fusion protein thereof.


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