The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2024
Filed:
Feb. 05, 2019
Applicant:
Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;
Inventors:
Stefano Gustincich, Trieste, IT;
Silvia Zucchelli, Trieste, IT;
Peter Podbevsek, Trieste, IT;
Janez Plavec, Trieste, IT;
Piero Carninci, Yokohama, JP;
Hazuki Takahashi, Trieste, IT;
Toshio Yamazaki, Trieste, IT;
Takako Ohyama, Trieste, IT;
Harshita Sharma, Trieste, IT;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/67 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/67 (2013.01); C12N 2310/11 (2013.01); C12N 2310/531 (2013.01); C12N 2310/532 (2013.01); C12N 2320/11 (2013.01);
Abstract
There are disclosed functional nucleic acid molecules comprising a target binding sequence comprising a sequence reverse complementary to a target mRNA sequence for which protein translation is to be enhanced; and a regulatory sequence having two-dimensional structures comprising specific stem-loop and internal loop domains and displaying translation enhancing efficiency.