The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2024

Filed:

Jul. 25, 2019
Applicants:

Tel Hashomer Medical Research Infrastructure and Services Ltd., Ramat-Gan, IL;

Tageza Biopharmaceuticals Ltd., Tel Aviv, IL;

Inventors:

Benjamin Dekel, Tel-Aviv, IL;

Orit Harari-Steinberg, RaAnana, IL;

Sanja Goldberg, Ramat HaSharon, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/286 (2013.01); A61K 35/17 (2013.01); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); C12Q 1/6886 (2013.01); G01N 33/57492 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/70571 (2013.01);
Abstract

Methods of treating cancer are provided. Accordingly, there is provided a method of treating cancer in a subject in need thereof, the method comprising administering to the subject an effective amount of an agent capable of (i) specifically binding GABRA2, the agent comprising a therapeutic moiety; and/or (ii) downregulating activity and/or expression of said GABRA2. Also provided are compositions, article of manufactures and methods of diagnosing cancer and monitoring cancer treatment.


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