The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2024
Filed:
Jan. 05, 2024
Applicant:
Immunocore Limited, Oxon, GB;
Inventors:
Jakub Jaworski, Oxon, GB;
Kate Atkin, Oxon, GB;
Arnaud Techine, Oxon, GB;
Vijaykumar Karuppiah, Oxon, GB;
Florence Schlosser, Oxon, GB;
Ana Pereira Ribeiro, Oxon, GB;
Chandramouli Chillakuri, Oxon, GB;
Nathaniel Liddy, Oxon, GB;
Andrew Creese, Oxon, GB;
Martin Ebner, Oxon, GB;
Assignee:
IMMUNOCORE LIMITED, Oxon, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61P 35/00 (2018.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01);
Abstract
The present invention relates to binding molecules that comprise T cell receptor (TCR) variable domains and which can bind to a PRAME peptide-HLA complex. In particular, the present invention relates to binding molecules that bind to PYLGQMINL (SEQ ID NO: 1) in complex with HLA-A24. The invention also relates to the use of such molecules for the treatment of malignant diseases.