The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2024
Filed:
Jun. 13, 2019
Applicant:
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Inventors:
Yannick Jacques, Nantes, FR;
Ariane Plet, Nantes, FR;
Erwan Mortier, Nantes, FR;
Agnès Quemener, Nantes, FR;
Patricia Vusio, Saint Sébastien sur Loire, FR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); C07K 14/54 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7155 (2013.01); C07K 14/5443 (2013.01); C07K 2319/00 (2013.01);
Abstract
The present invention relates to the stimulation of the IL-15Rbeta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells. Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.