The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2024

Filed:

Dec. 08, 2020
Applicants:

Vladislav V. Verkhusha, Bronx, NY (US);

Olena S. Oliinyk, Helsinki, FI;

Inventors:

Vladislav V. Verkhusha, Bronx, NY (US);

Olena S. Oliinyk, Helsinki, FI;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/405 (2006.01); A61K 49/00 (2006.01); C12Q 1/6816 (2018.01);
U.S. Cl.
CPC ...
C07K 14/405 (2013.01); A61K 49/0045 (2013.01); C12Q 1/6816 (2013.01);
Abstract

This invention provides the nucleic acid molecules encoding novel small monomeric near-infrared fluorescent protein miRFP670nano, variants and derivatives thereof as well as proteins and peptides encoded by these nucleic acids. The invention also relates to derivatives, homologues, or mutants of the specific proteins referenced above as well as fragments of the nucleic acids and the peptides encoded thereby. The invention further relates to host-cells, stable cell lines and transgenic organisms comprising above-referenced nucleic acid molecules. The present invention also refers to methods of making and using small monomeric near-infrared fluorescent proteins derived from cyanobacteriochromes. The presented protein and its derivatives find use in a variety of applications and approaches, including labeling of biomolecules, cells or cell organelles, detecting protein-protein interactions, and generation of genetically encoded fluorescent biosensors.


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Verkhusha, Vladislav. (2024). Small near-infrared fluorescent proteins developed from cyanobacteriochrome (U.S. Patent No. 12134634). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12134634

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