The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2024
Filed:
Nov. 09, 2018
Applicant:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Inventor:
Geeta Upadhyay, Washington, DC (US);
Assignee:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 219/10 (2006.01); C07C 39/15 (2006.01);
U.S. Cl.
CPC ...
C07D 219/10 (2013.01); C07C 39/15 (2013.01);
Abstract
The present technology relates to compounds that inhibit human Ly6K and homologs thereof. Also disclosed are methods of using such compounds to: inhibit activity of a Ly6K protein in a cell; decrease migration, colony formation, and/or proliferation of a cell; modulate expression of a gene in a cell, reduce suppression of the immune response to cancer in a subject, decrease tumorigenic growth of a cancer in a subject, and treat or prevent in a subject a disorder mediated by Ly6K protein.