The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2024

Filed:

Nov. 16, 2022
Applicant:

Biontech SE, Mainz, DE;

Inventors:

Ugur Sahin, Mainz, DE;

Alptekin Güler, Mainz, DE;

Andreas Kuhn, Mainz, DE;

Alexander Muik, Seeheim-Jugenheim, DE;

Annette Vogel, Mainz, DE;

Kerstin Walzer, Seeheim-Jugenheim, DE;

Sonja Witzel, Bad Vilbel, DE;

Stephanie Hein, Rüsselsheim, DE;

Özlem Türeci, Mainz, DE;

Assignee:

BioNTech SE, Mainz, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 9/51 (2006.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 31/7115 (2006.01); A61K 31/712 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/215 (2006.01); A61P 31/14 (2006.01); A61P 35/00 (2006.01); B82Y 5/00 (2011.01); C12N 7/00 (2006.01); C12N 15/11 (2006.01); C12N 15/67 (2006.01); C12N 15/88 (2006.01); C12P 19/34 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0066 (2013.01); A61K 9/0019 (2013.01); A61K 9/1271 (2013.01); A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 31/7088 (2013.01); A61K 31/7105 (2013.01); A61K 31/711 (2013.01); A61K 31/7115 (2013.01); A61K 31/712 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 39/215 (2013.01); A61K 48/0033 (2013.01); A61P 31/14 (2018.01); A61P 35/00 (2018.01); B82Y 5/00 (2013.01); C12N 7/00 (2013.01); C12N 15/11 (2013.01); C12N 15/67 (2013.01); C12N 15/88 (2013.01); C12P 19/34 (2013.01); A61K 38/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55555 (2013.01); C12N 2770/18022 (2013.01); C12N 2770/18034 (2013.01); C12N 2770/18071 (2013.01); C12N 2770/20034 (2013.01); C12N 2840/00 (2013.01);
Abstract

This disclosure relates to the field of RNA to prevent or treat coronavirus infection. In particular, the present disclosure relates to methods and agents for vaccination against coronavirus infection and inducing effective coronavirus antigen-specific immune responses such as antibody and/or T cell responses. Specifically, in one embodiment, the present disclosure relates to methods comprising administering to a subject RNA encoding a peptide or protein comprising an epitope of SARS-CoV-2 spike protein (S protein) for inducing an immune response against coronavirus S protein, in particular S protein of SARS-CoV-2, in the subject, i.e., vaccine RNA encoding vaccine antigen.


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