The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2024
Filed:
Nov. 02, 2021
Industry Foundation of Chonnam National University, Gwangju, KR;
Korea Institute of Medical Mcrorobotics, Gwangju, KR;
Johns Hopkins University, Baltimore, MD (US);
Eun Pyo Choi, Gwangju, KR;
Jong Oh Park, Gyeonggi-do, KR;
Chang Sei Kim, Gwangju, KR;
You Hee Choi, Gwangju, KR;
Byung Jeon Kang, Gwangju, KR;
Ho Yong Kim, Gwangju, KR;
Hyeong Woo Song, Jeollanam-do, KR;
Dae Won Jung, Gwangju, KR;
Han Sol Lee, Gyeonggi-do, KR;
Deok Ho Kim, Ellicott City, MD (US);
Min Jae Do, Baltimore, MD (US);
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, Gwangju, KR;
KOREA INSTITUTE OF MEDICAL MICROROBOTICS, Gwangju, KR;
Johns Hopkins University, Baltimore, MD (US);
Abstract
Disclosed herein are a microbubble-extracellular vesicle complex, a production method therefor, and a system for driving the same. In one aspect, preferred microbubble-extracellular vesicle complexes may comprise an ultrasound contrast agent-based microbubble, an extracellular cell derived from a natural killer cell (NK cell), a human glial cell, or a human mesenchymal stem cell, and a coupling medium and can be derive in a 3D mode using ultrasonic waves and deliver a drug loaded in the extracellular vesicle to a target site.