The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2024
Filed:
Nov. 04, 2020
Applicant:
Epivario, Inc., Philadelphia, PA (US);
Inventors:
Philippe Nakache, Ness Ziona, IL;
Omri Erez, Rehovot, IL;
Simone Botti, Rehovot, IL;
Andreas Goutopoulos, Boston, MA (US);
Assignee:
EpiVario, Inc., Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 31/4152 (2006.01); A61K 31/4155 (2006.01); A61K 31/4184 (2006.01); A61K 31/422 (2006.01); A61K 31/4245 (2006.01); A61K 31/4439 (2006.01); A61K 31/497 (2006.01); A61K 31/498 (2006.01); A61K 31/635 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/501 (2013.01); A61K 31/4152 (2013.01); A61K 31/4155 (2013.01); A61K 31/4184 (2013.01); A61K 31/422 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/498 (2013.01); A61K 31/635 (2013.01); A61P 35/04 (2018.01);
Abstract
The present invention relates to novel ACSS2 inhibitors having activity as anti-cancer therapy, treatment of alcoholism, and viral infection (e.g., CMV), composition and methods of preparation thereof, and uses thereof for treating viral infection, alcoholism, alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), obesity/weight gain, anxiety, depression, post-traumatic stress disorder, inflammatory/autoimmune conditions and cancer, including metastatic cancer, advanced cancer, and drug resistant cancer of various types.