The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Jul. 28, 2023
Aligos Therapeutics, Inc., South San Francisco, CA (US);
Leonid Beigelman, San Mateo, CA (US);
Vivek Kumar Rajwanshi, Cupertino, CA (US);
Markus Hossbach, Kulmbach, DE;
Rajendra K. Pandey, Foster City, CA (US);
Jin Hong, Pacifica, CA (US);
Laxman Eltepu, San Ramon, CA (US);
Saul Martinez Montero, San Bruno, CA (US);
N. Tilani S. De Costa, South San Francisco, CA (US);
Aligos Therapeutics, Inc., South San Francisco, CA (US);
Abstract
Disclosed herein are short interfering nucleic acid (siNA) molecules comprising modified nucleotides and uses thereof. The siNA molecules may be double stranded and comprise modified nucleotides selected from 2'-O-methyl nucleotides and 2′-fluoro nucleotides. Further disclosed herein are siNA molecules comprising (a) a phosphorylation blocker, conjugated moiety, or 5′-stabilized end cap; and (b) a short interfering nucleic acid (siNA).