The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2024

Filed:

Feb. 10, 2023
Applicants:

Florida Atlantic University Board of Trustees, Boca Raton, FL (US);

University of Florida Research Foundation, Gainesville, FL (US);

Inventors:

Predrag Cudic, Boca Raton, FL (US);

Jay McLaughlin, Gainesville, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); A61K 9/00 (2006.01); A61K 47/64 (2017.01); A61K 47/65 (2017.01); A61P 25/04 (2006.01); A61P 25/06 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/28 (2006.01); A61P 25/36 (2006.01); C07K 5/12 (2006.01); C07K 7/64 (2006.01); A61K 38/00 (2006.01); C40B 40/10 (2006.01);
U.S. Cl.
CPC ...
C07K 5/12 (2013.01); A61K 9/0043 (2013.01); A61K 31/4045 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61P 25/04 (2018.01); A61P 25/06 (2018.01); A61P 25/16 (2018.01); A61P 25/18 (2018.01); A61P 25/28 (2018.01); A61P 25/36 (2018.01); C07K 7/64 (2013.01); A61K 38/00 (2013.01); C40B 40/10 (2013.01);
Abstract

Novel cyclic peptides, cyclic peptide conjugates and compositions containing them for treating neurological diseases in a subject include an Odorranalectin (OL) sequence or modified OL sequence as a scaffold and a biologically active peptide or protein and/or therapeutic agent conjugated thereto. Methods of treatment of neurological diseases are based on intranasal delivery of a cyclic peptide or cyclic peptide conjugate as described herein. Combinatorial libraries that include a plurality of cyclic peptides have also been developed and can be used to screen for a ligand(s) for a receptor of interest.


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