The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Mar. 21, 2024
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Saul J. Priceman, Valley Village, CA (US);
John P. Murad, Diamond Bar, CA (US);
Eric Lee, Diamond Bar, CA (US);
Assignee:
City of Hope, Duarte, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/24 (2006.01); C07K 14/54 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 14/5434 (2013.01); C12N 5/0636 (2013.01); C07K 2319/02 (2013.01);
Abstract
This disclosure relates to, inter alia, cells expressing both a chimeric antigen receptor (CAR) and membrane bound IL-12 and the use of these cells to target and treat cancers (e.g., solid tumors and cancers expressing CD19, CD22, BCMA, PSCA, HER2, TAG-72, and PSCA). The disclosure also relates to cells expressing a membrane bound IL-12.