The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2024

Filed:

Mar. 29, 2022
Applicant:

Sage Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Ravindra B. Upasani, San Jose, CA (US);

Boyd L. Harrison, Princeton Junction, NJ (US);

Benny C. Askew, Marshfield, MA (US);

Jean-Cosme Dodart, Brookline, MA (US);

Francesco G. Salituro, Marlborough, MA (US);

Albert Jean Robichaud, Boston, MA (US);

Assignee:

SAGE THERAPEUTICS, INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07J 41/00 (2006.01); C07J 1/00 (2006.01); C07J 3/00 (2006.01); C07J 7/00 (2006.01); C07J 9/00 (2006.01); C07J 31/00 (2006.01); C07J 43/00 (2006.01); C07J 75/00 (2006.01);
U.S. Cl.
CPC ...
C07J 41/00 (2013.01); C07J 1/00 (2013.01); C07J 1/0029 (2013.01); C07J 3/00 (2013.01); C07J 7/007 (2013.01); C07J 9/00 (2013.01); C07J 9/005 (2013.01); C07J 31/003 (2013.01); C07J 31/006 (2013.01); C07J 41/0005 (2013.01); C07J 41/0011 (2013.01); C07J 41/0055 (2013.01); C07J 43/003 (2013.01); C07J 75/00 (2013.01);
Abstract

Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, wherein Z is a group of the formula (i), (ii), (iii), (iv), or (v), and wherein L, L, L, X, X, Y, R, R, R, n, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, and Rare as defined herein, and pharmaceutical compositions thereof. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions in mammals.


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